Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用
2-Methoxy Canagliflozin is an impurity of Canagliflozin (CAT# C175190), which is a sodium-?glucose cotransporter-?2 inhibitor (SGLT2i) useful in the treatment of type 2 diabetes and proven to ameliorate kidney and heart failure in patients with type 2 diabetes. It can be useful in the synthesis and optimization of Canagliflozin.
參考文獻
Minami, T., et al.: Expert Opin. Pharmacother., 22, 2087 (2021); Wada, T., et al.: J. Diabetes Invest., 13, 54 (2022); Sen, T., et al.: J. Am. Heart Assoc., 10, e021661 (2021); Metil, D. S., et al.: Org. Process Res. Dev., 22, 27 (2018)
滬ICP備17019645號
400-821-0725
