Phenylguanidine is used to prepare (4-Aminomethyl)phenylguanidine derivative, which is a nonpeptidic highly selective inhibitor of human urokinase. A series of substituted phenylguanidine compounds are selective inhibitors of urokinase.
參考文獻
Sperl, S., et al.: Proc. Natl. Acad. Sci. USA, 97, 5113 (2000); Yang, H., et al.: J. Med. Chem., 33, 2956 (1990);
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